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Split hand sign is a classic clinical sign seen in Motor Neuron Disease (MND), especially Amyotrophic Lateral Sclerosis (ALS). 🔍 What is it? It refers to selective wasting and weakness of: Thenar muscles (Abductor Pollicis Brevis) First dorsal interosseous (FDI) With relative sparing of: Hypothenar muscles (especially Abductor Digiti Minimi) ➡️ This creates the appearance of the hand being “split” into wasted and preserved muscle groups. ✋ Muscles Involved Wasted Spared Thenar muscles Hypothena
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Split hand sign is a classic clinical sign seen in Motor Neuron Disease (MND), especially Amyotrophic Lateral Sclerosis (ALS). 🔍 What is it? It refers to selective wasting and weakness of: Thenar muscles (Abductor Pollicis Brevis) First dorsal interosseous (FDI) With relative sparing of: Hypothenar muscles (especially Abductor Digiti Minimi) ➡️ This creates the appearance of the hand being “split” into wasted and preserved muscle groups. ✋ Muscles Involved Wasted Spared Thenar muscles Hypothena
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Dr. Neuro on Instagram: "Thenar atrophy in MND (Motor Neuron Disease) is a classical lower motor neuron (LMN) sign, especially seen in ALS (Amyotrophic Lateral Sclerosis). 🔹 Why does thenar atrophy occur in MND? Thenar muscles are supplied mainly by the median nerve (C8–T1) In MND, there is degeneration of anterior horn cells This causes: Denervation Muscle wasting Weakness of thumb movements 🔹 Muscles involved (Thenar eminence) Abductor pollicis brevis Opponens pollicis Flexor pollicis brevis
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