Cancer cell biology: mutated KRAS & reciprocal signalling
2:25
YouTubeThe Institute of Cancer Research, London
Cancer cell biology: mutated KRAS & reciprocal signalling
This video was originally published by Phospho Biomedical Animation on 14/04/16 on this page: https://youtu.be/GU-QZp5FwM8 Across a wide variety of cancer types, a protein called KRAS can get hyperactivated and transmit an overload of unwanted growth signals to the cells, causing them to divide and form a tumour. A tumour doesn't just contain ...
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Adagrasib is an inhibitor of mutant KRAS G12C. The efficacy of adagrasib in the treatment of KRAS G12C–mutated colorectal cancer, used either alone or with cetuximab, has been uncertain. New research findings are summarized in a short video. https://nej.md/3vANNHq | The New England Journal of Medicine
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Adagrasib is an inhibitor of mutant KRAS G12C. The efficacy of adagrasib in the treatment of KRAS G12C–mutated colorectal cancer, used either alone or with cetuximab, has been uncertain. New research findings are summarized in a short video. https://nej.md/3vANNHq | The New England Journal of Medicine
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Tissue samples of arteriovenous malformations of the brain were obtained from 72 patients. The majority of the samples had an activating mutation in KRAS, a gene previously implicated in tumorigenesis. Video: Phenotype of Endothelial Cells after KRAS Activation. Full study: http://nej.md/2CzIBdQ | The New England Journal of Medicine
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What does a RAS mutation mean, and what is a KRAS biomarker? Watch the video to learn more about this gene, and visit our website to learn about when and how you should have biomarker testing for a RAS gene, the treatment options if you have a mutation, and what to ask your doctor: bit.ly/BiomarkerKRAS Special thanks to Amgen for supporting the development of this educational material. | Colorectal Cancer Alliance
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