In contrast, substances that bind directly to an enzyme's active site or the binding site of the endogenous ligand of a receptor are called orthosteric regulators or modulators. The site to …

Jul 26, 2025 · Allosteric regulation is a biological mechanism that controls protein activity, often enzymes, through the binding of molecules at a site distinct from the active site. This process …

The meaning of ALLOSTERIC is of, relating to, undergoing, or being a change in the shape and activity of a protein (such as an enzyme) that results from combination with another substance …

“Allosteric” was first introduced to mean the other site (i.e., a site distinct from the active or orthosteric site), an adjective for “regulation” to imply a regulatory outcome resulting from …

Allosteric control, in enzymology, inhibition or activation of an enzyme by a small regulatory molecule that interacts at a site (allosteric site) other than the active site (at which catalytic …

Allosteric regulation is a process by which the activity of a protein or enzyme is modulated by the binding of an effector molecule at a site other than the active site, known as the allosteric site.

Allosteric regulation is classically defined as action at a distance, where a perturbation outside of a protein active site affects function.