BACKGROUND: The disruption of the blood–brain barrier (BBB) is a central pathogenic event in many central nervous system disorders. However, the mechanisms regulating BBB function remain incompletely ...

Proteins are the molecular machines of cells. They are produced in protein factories called ribosomes based on their ...

Protein folding helpers such as TRiC and prefoldin (PFD) are crucial for the correct folding of many essential proteins. In a Nature study, researchers from the Max Planck Institute of Biochemistry ...

How physically magnifying objects using a key ingredient in diapers has opened an unprecedented view of the microbial world.

For the first time, scientists have discovered evidence of bacteria hiding in 'noninfectious' kidney stones. These hardened ...

Microphysiological systems and organ-on-chip technologies are increasingly used to model human tissues outside the body, offering alternatives to animal experiments and traditional cell cultures.

Understanding how living tissues function over time is essential for studying disease mechanisms, evaluating drug responses, and developing advanced ...

By combining two fundamentally different microscopy techniques, researchers can now measure the optical properties of a ...

These include stress granules and proteasome storage granules (PSGs). In the past, these membraneless organelles were only visible as “droplets” using a fluorescence microscope. Now, researchers from ...

The findings are significant as infections caused by S. aureus are becoming harder to treat due to rising antibiotic resistance and the lack of an approved vaccine.S. aureus is responsible for a wide ...

In research that could shed light on the growth and formation of complex tissue architectures, Brown University engineers ...

The authors present convincing data to validate abscisic acid-induced dimerisation to induce a synthetic spindle assembly checkpoint (SAC) arrest that will be of particular importance to analyse ...