BACKGROUND: The disruption of the blood–brain barrier (BBB) is a central pathogenic event in many central nervous system disorders. However, the mechanisms regulating BBB function remain incompletely ...

A microscopic parasite that quietly settles into the brain of humans and animals is not nearly as quiet as scientists once ...

Cancer immunotherapy has transformed modern oncology by harnessing the body's own immune system to combat malignant disease. Immune checkpoint inhibitors targeting the PD-1/PD-L1 pathway have produced ...

Bacteria in the human gut can directly deliver proteins into human cells, actively shaping immune responses. A consortium led ...

The Central Drugs Standard Control Organisation (CDSCO) has granted multiple CT-18 approvals between January 2020 and ...

Sermorelin, a synthetic analog of growth hormone–releasing hormone (GHRH 1–29), has long attracted scientific interest due to its structural fidelity to the endogenous GHRH fragment responsible for in ...

The study presents valuable findings of an optimized E. coli cell-free protein synthesis (eCFPS) system that has been simplified by reducing the number of core components from 35 to 7; furthermore, ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells. How genes are turned on ...

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The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...