A research team from POSTECH and ImmunoBiome in Korea, led by Professor Sin-Hyeog Im, has uncovered a new mechanism showing ...
Background The pathogenesis of liver fibrosis centres on the activation of hepatic stellate cells (HSCs). Adenosine-to-inosine RNA editing, primarily catalysed by adenosine deaminase acting on RNA1 ...
Researchers discovered a way to keep T cells from wearing out during the fight against cancer, and the approach could make immune-based treatments far more powerful. They found that tumors use a ...
cDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China dDepartment of General Surgery, The ...
Antigen presenting cells capture tumour antigen within the tumour microenvironment and migrate to tumour-draining lymph nodes where they prime tumour-reactive T cells. Tumour-reactive T cells then ...
Hypertension is a major cause of chronic kidney disease. It triggers an innate immune response that leads to further damage to the kidney's vasculature, resulting in dysfunction. We, along with others ...
As a proof-of-concept, the research team recreated liver injury triggered by the antibiotic flucloxacillin, which occurs only in carriers of the HLA-B*57:01 risk gene. The model reproduced hallmark ...
A Johns Hopkins All Children’s Hospital team found that “hot-wiring” the immune microenvironment in mouse tumors, by co-activating STING and LTβR, rapidly recruits T and B cells, builds in-tumor ...
In a new study, @HopkinsMedicine researchers found a way to build lasting tumor-fighting immunity and prevent cancer recurrence by turning “immune cool” tumors into “immune hot” ones. › In experiments ...
CULVER CITY, Calif.--(BUSINESS WIRE)--ImmunityBio, Inc. (NASDAQ: IBRX), a leading immunotherapy company, today announced new paradigm changing findings from the Phase 2 QUILT-3.055 study, ...
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