For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

A groundbreaking gene-editing method from UT Austin is changing the game for treating complex genetic diseases like cystic fibrosis, hemophilia, and Tay Sachs. Using retrons—DNA tools borrowed from ...

The authors attempt to use sequencing of nascent DNA (DNA linked to an RNA primer, "SNS-Seq") to localise DNA replication origins in Trypanosoma brucei, but they analyse the results for only part of ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

The Age of AI will rely on massive volumes of data that can be easily stored and retrieved—and bioscience may have an ingenious solution. A scientist examines a DNA (deoxyribonucleic acid) profile on ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Russell has a PhD in the history of medicine, violence, and colonialism. His research has explored topics including ethics, science governance, and medical involvement in violent contexts. Russell has ...

Multiomic profiling of LRRC15 in triple negative breast cancer (TNBC). A phase 1b study of Plk1 inhibitor onvansertib in combination with paclitaxel in metastatic triple-negative breast cancer (mTNBC) ...

Scientists have uncovered the locations of mysterious DNA shapes across great ape genomes, potentially reshaping our understanding of genetic function and evolution. Researchers utilized recently ...