RMD Open

Pre-arthritis stages of rheumatoid arthritis: from pathology to precision prevention

Over the last decade, the outlook for patients with rheumatoid arthritis (RA) has improved, but there is growing interest in ...
RMD Open

Early methylprednisolone pulses and prevention of long-term damage accrual in active systemic lupus erythematosus: a propensity score analysis of the Lupus–Cruce…

Objective Methylprednisolone pulses (MP) help achieve prolonged remission in patients with moderate–severe systemic lupus ...
RMD Open

Sustaining remission in rheumatoid arthritis: the role of clinical deep remission and its implications for drug tapering

Objective While sustained remission is the treatment goal for rheumatoid arthritis (RA), its long-term remission remains ...
RMD Open

Heat-not-burn tobacco induces protein post-translational modifications and apoptosis in bronchial cells: possible role in rheumatoid arthritis

Objectives Smoking is recognised as one of the strongest environmental risk factors for the development of rheumatoid ...
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Diagnostic issues in difficult-to-treat rheumatoid arthritis: a systematic literature review informing the EULAR recommendations for the management of difficult-to-treat ...

Objectives To summarise the evidence on diagnostic issues in difficult-to-treat rheumatoid arthritis (D2T RA) informing the EULAR recommendations for the management of D2T RA. Methods A systematic ...
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Development and validation of a new ultrasound score (SONAR-7) for synovitis in psoriatic arthritis and axial spondyloarthritis

Objectives Development of a new ultrasound (US) synovitis score (SONography in Arthritis and Rheumatism (SONAR)-7) with evaluation of its diagnostic performance in a cohort of patients with psoriatic ...
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Prevalence and clinical characteristics of patients with rheumatoid arthritis with interstitial lung disease using unstructured healthcare data and machine learning

Objectives Real-world data regarding rheumatoid arthritis (RA) and its association with interstitial lung disease (ILD) is still scarce. This study aimed to estimate the prevalence of RA and ILD in ...
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Trajectory analysis of glucocorticoid treatment highlights issues in the current tapering strategy for polymyalgia rheumatica

Objectives To identify glucocorticoid (GC) treatment patterns in patients with polymyalgia rheumatica (PMR) and explore patient profiles that may benefit from GC-sparing interventions. Methods This ...
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Efficacy and safety of filgotinib in methotrexate-naive patients with rheumatoid arthritis with poor prognostic factors: post hoc analysis of FINCH 3

Objective This analysis evaluated efficacy and safety of filgotinib, a Janus-associated kinase 1-preferential inhibitor, in methotrexate (MTX)-naive patients with rheumatoid arthritis (RA) with ...
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Inflammatory rheumatic diseases with onset after SARS-CoV-2 infection or COVID-19 vaccination: a report of 267 cases from the COVID-19 and ASD group

Objectives To better define the spectrum of new-onset post-COVID-19 and post-COVID-19 vaccine inflammatory rheumatic diseases (IRD) from a large multicentric observational study. Methods Consecutive ...
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Long-term safety and effectiveness of canakinumab therapy in patients with cryopyrin-associated periodic syndrome: results from the β-Confident Registry

Objective To report the long-term safety and effectiveness of canakinumab, a fully human anti-interleukin 1β monoclonal antibody, in patients with cryopyrin-associated periodic syndromes (CAPS), ...
rmdopen.bmj

Deep learning algorithm for semiquantification of spinal inflammation in axial spondyloarthritis

Objective To develop a deep learning algorithm for semiquantification of spinal inflammation in patients with axial spondyloarthritis (SpA). Methods The study included 330 participants with axial SpA.