Introduction: Lung cancer is a highly heterogeneous disease, and the tumor microenvironment (TME) characteristics are closely related to disease progression and treatment outcomes. We elucidated the ...

Researchers have sequenced the oldest RNA ever recovered, taken from a woolly mammoth frozen for nearly 40,000 years. The RNA reveals which genes were active in its tissues, offering a rare glimpse ...

It was 2012 when Love Dalén, a paleogeneticist at Stockholm University, first laid eyes upon a special specimen on a lab table in eastern Siberia. "Our Russian collaborators said, 'Come here into this ...

A woolly mammoth that was frozen in the Siberian permafrost for nearly 40,000 years has yielded the world’s oldest RNA. The specimen, found in 2010 and nicknamed Yuka, is regarded as the ...

In 2010 Yukaghir hunters found the nearly intact carcass of a young woolly mammoth frozen in the northern Siberian permafrost. With its reddish-brown fur still clinging to its skin, the dog-sized calf ...

Immunotherapy has been a revolutionary breakthrough for cancer therapeutics, but it is still hampered in that it only benefits certain patients. Moreover, the molecular determinants of immunotherapy ...

The NovaSeq X Plus is a half-ton machine that looks like an industrial freezer, with a big touchscreen on top and racks to hold cartridges of chemicals below. Its job is to simultaneously sequence 128 ...

Abstract: Recently, with the growth of the required data size for emerging applications (e.g., graph processing and machine learning), the von Neumann bottleneck has become a main problem for ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Learn to crochet a heart-shaped bag and matching pouch using pixel grid tapestry techniques. Perfect for beginners and crafters looking for detailed, step-by-step instructions. #CrochetTutorial ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

For centuries, scientists have recognized that certain illnesses can run in families, an idea that dates back to Hippocrates. Over time, researchers have become increasingly skilled at uncovering how ...