When two defective gene variants combine, normal protein function can sometimes be restored.

Can the brain keep working when its architecture changes? Researchers at the University of Geneva (UNIGE) have discovered ...

This article was reviewed by Felix Gussone, MD. Key Takeaways: Cholesterol is a key building block for testosterone. Through ...

A multidisciplinary team has developed a selective compound that inhibits an enzyme tied to inflammation in people at genetic ...

After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, forms an abnormal connection with an enzyme called ClpP. This enzyme normally ...

Doctors in Lucknow successfully treated a young woman born with two uteruses and two vaginas through a series of rare, ...

Dewpoint has selected a novel small molecule to prevent the formation of abnormal TDP-43 protein clumps in ALS and other ...

Researchers at Karolinska Institutet have discovered that even slight abnormalities in kidney function—within the normal ...

A treatment that restores normal kidney function in almost half of patients with lupus nephritis has been approved by the National Institute for Health and Care Excellence (NICE). Obinutuzumab ...

Researchers have identified a key molecular interaction that accelerates Parkinson’s disease by damaging the brain’s energy ...

Roche's Gazyvaro, a drug that can restore kidney function in people living with lupus nephritis, has been cleared for use by ...

Neural tissue normally dies quickly without oxygen. Yet bird retinas—among the most energy-demanding tissues in the animal ...