This review maps key bottlenecks in turning fragment hits into lead compounds and highlights emerging solutions: integrated Design-Make-Test cycles, high-throughput assays, automation and modelling to ...
In 1992 the National Transportation Safety Board (NTSB) commissioned a report to study the causes of wheel separations from medium and heavy duty trucks. The report showed that on average between 750 ...
Abstract: With the rapid development of artificial intelligence technology, machine learning has been increasingly applied in engineering fields. The application of machine learning methods to ...
Abstract: Cyclic peptides become attractive therapeutic candidates due to their diverse biological activities. However, existing deep learning-based sequence design models, such as ProteinMPNN, are ...
With challenging coursework, wide-ranging options for specialization, and state-of-the-art facilities, our students become effective engineers and future leaders. Join one of the largest mechanical ...
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