Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid ...

Lipids are fatty compounds that perform a range of essential functions in the body. Phospholipids, steroids, and triglycerides are examples of lipids. Although lipids play an essential role in the ...

Plant biology has long recognized the significance of surface lipid barriers—namely cuticles and suberin—as fundamental adaptations for terrestrial life.

Fig. 2 Examples of ionizable lipids, sterols, phospholipids, and PEG-lipids used in LNP formulations. Created with BioRender.com. Fig. 3 High-throughput screening of the 3-component ionizable ...

A genetic disorder leads to an increase in bioactive lipids in the brain, resulting in an imbalance between excitation and inhibition in neural circuits and promoting mental disorders. However, ...

A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast cancer is fueled by lipids and that these fatty acids are a key feature of obesity that ...