A study maps how toxic tau disrupts synapses over time, showing early postsynaptic damage that later spreads presynaptically.

A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction ...

As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why.

Johns Hopkins scientists reveal that “inactive” GluD brain proteins regulate neuronal communication and open up new ...

As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why. It is increasingly clear, though, that the loss of synapses-the flexible and adaptive relay ...

Congenital stationary night blindness (CSNB) is caused by mutations in a specific calcium channel. A comprehensive proteomic study by researchers at the University of Innsbruck now reveals how these ...

Alzheimer’s may destroy memory by flipping a single molecular switch that tells neurons to prune their own connections. Researchers found that both amyloid beta and inflammation converge on the same ...

Scientists uncover new synapse hotspots in the teen brain, challenging the old theory of synaptic pruning and its link to schizophrenia.

Researchers from Ulsan National Institute of Science and Technology (UNIST) designed a biodegradable, energy efficient ...

Scientists at Johns Hopkins have uncovered a surprising new way to influence brain activity by targeting a long-mysterious class of proteins linked to anxiety, schizophrenia, and movement disorders.

The next time you reach for a memory or make a quick choice, a storm of tiny signals races through your brain. Scientists can usually see only half of that storm. Now, a new engineered protein finally ...