Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Notably, inhibition of cGAS-STING from early development rescued mice from developmental lethality and premature aging caused ...

A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.

DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that aid DNA in carrying out essential processes such as replication, repair, and ...

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...

A new study finds that a trait helping a marine bacterium survive and flourish today may ultimately become its Achilles Heel as ocean conditions continue to shift.

Common ocean bacteria struggle to divide when conditions change, reshaping how warming seas affect ecosystems.

A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature ...

A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published in Nature ...

By selectively blocking the ATAC complex via its unique YEATS2 subunit, a new inhibitor turns off tumor-promoting genes, ...