Explore the role of transcription factor biology in drug discovery and how it impacts our understanding of disease mechanisms ...

DNA can be thought of as a vast library that stores all genetic information. Cells do not use this information all at once.

Bacterial transcription is a production line of copying over genetic instructions from double stranded DNA to produce RNA, which is then used for the subsequent production of proteins that the ...

Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown ...

A new paradigm has emerged in biology in which RNA molecules are active participants in regulating, catalysing and controlling many reactions that define fundamental processes in cells — roles that in ...

Scientists used the auxin-inducible degron 2 system on CTCF, bringing the novel approach to bear on a fundamental protein. CTCF is a critical protein known to play various roles in key biological ...

Transcription factors are an essential part of gene expression. Some of these proteins are known as master regulators, and they can have an impact on many different biochemical pathways and processes ...