Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...

A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival, revealing a potential strategy for selectively targeting tumours associated with ...

Cell death research has emerged as a cornerstone for understanding the pathogenesis of neurological disorders. Neurons and glial cells in the central ...

Necrotic cell death is a fundamental biological process, yet the terminal execution mechanisms of necrosis are still not ...

Here’s what you’ll learn when you read this story: When cells are about to die, they send signals that trigger proteins which are supposed to destroy them, but it doesn’t always happen that way. Some ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in ACS Nano, how proteins in cells can be controllably activated through heating, an effect that can be used ...

Researchers have discovered that a key protein, cFLIP, is essential for regulating programmed cell death in lymphoma cells. This discovery provides insights into the mechanisms of this cancer’s cell ...

After cells die, they leave a residue that sends messages to other cells in ways that are valuable to the immune system. But this process can also be hijacked by viruses such as influenza, according ...