The majority of base pairs in double-stranded DNA exist in the canonical Watson-Crick geometry. However, they can also adopt alternate Hoogsteen conformations in various complexes of DNA with proteins ...
James Watson, who has died aged 97, was the 25-year-old American biologist who in 1953, with Francis Crick, revealed the double helix structure of DNA, the chemical of which genes are made; for this ...
For James Watson, DNA was everything — not just his life's work, but the secret of life itself. Over his long and storied career, Watson arguably did more than any other scientist to transform a ...
In 1953, when he was not yet 25 years old, Watson worked with English researcher Francis Crick to piece together clues from various experiments — including work done by X-ray crystallographer Rosalind ...