In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...
Heart disease remains the leading cause of death worldwide, yet progress in understanding and treating cardiac disorders is ...
Mechanical cues are key regulators of cardiac development, yet their role in organoid maturation remains underexplored. In a ...
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Gene therapy for sickle cell and β-thalassemia works by disrupting three-dimensional genome structure
Scientists at St. Jude Children's Research Hospital and Northwestern University identified a previously unknown treatment opportunity for sickle cell disease and β-thalassemia. The discovery, ...
Measuring membrane thickness was previously only possible in artificial membranes—now scientists can do it inside intact ...
(PhysOrg.com) -- For the first time, scientists have developed a method for generating accurate three-dimensional models of the entire DNA strand of a cell, known as a genome.
Explore the potential of heart organoids in understanding cardiac disorders and developing new treatment methods.
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First human 'lung-on-chip' model developed using stem cells from a single donor
Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.
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