Small, biologically inert molecules can be converted into bioactive degraders that selectively downregulate disease-causing RNAs. By attaching an RNA molecular recognition element to a second compound ...

Ribonucleic acids (RNAs), which decode the genetic code stored in DNA and produce proteins, fold into diverse structures to govern fundamental biological processes in all life forms, including humans.

KYOTO & FUJISAWA, Japan--(BUSINESS WIRE)--xFOREST Therapeutics Co., Ltd. (“xFOREST”) and Axcelead Drug Discovery Partners, Inc. (“Axcelead DDP”) today announced the launch of a joint research ...

The human genome has just over 20,000 genes coding for proteins. Yet, it produces at least ten times that many different non-coding RNA molecules, which can often take on more than one shape. At least ...

(Nanowerk Spotlight) Nucleic acids are becoming increasingly popular for assembling nanoscale structures, thanks to their programmable dimensionality and direct applications in the biological field.

Japan biotech xFOREST Therapeutics is teaming up with a drug discovery solutions provider in a research pact aiming to develop new RNA structure-targeted small molecule therapeutics, including mRNA ...

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved ...

Direct Cloning from any Cell or Tissue Source in any Species Is Promoted In the early 1990s Victor Ambros’ laboratory, then at Harvard University, identified a transcript in Caenorhabditis elegans ...

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for ...

Molecular geneticists describe ways to develop the -- as yet largely untapped -- potential of RNA structures. The human genome has just over 20,000 genes coding for proteins. Yet, it produces at least ...