Engineered BiTE molecule draws T cells to eliminate FAP+ modulated smooth muscle cells, reducing plaque burden across mouse atherosclerosis models.

Scientists have designed an immunotherapy that reduces plaque in the arteries of mice, presenting a possible new treatment strategy against heart disease. The antibody-based therapy could complement ...

Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the ...

Scientists have designed an immunotherapy that reduces plaque in the arteries of mice, presenting a possible new treatment strategy against heart ...

SLC44A2 controls vascular smooth muscle cells and is key for controlling aortic aneurysm Aug. 28, 2024 ...

The research was led by Professor Wang Lixin (Department of Vascular Surgery, Zhongshan Hospital, Fudan University) and Professor Zhou Bin (Shanghai Institute of Biochemistry and Cell Biology, Center ...

- Muscle cells, also known as myocytes, are specialized cells designed for contraction and force production. Skeletal Muscle Cells: These cells are long, cylindrical, and have a striated (or striped) ...

Cardiologists have spent decades trying to stabilize the fatty plaques that clog arteries, but a new wave of immunotherapy is going after the diseased cells at the heart of the problem. In mice, an ...