Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

A. Preview of timsTOF Ultra 2 system with novel Athena Ion Processor (AIP): - Improves protein group identification in single-cell proteomics (SCP) by 15%-20%, and ...

The capability to sort single cells of interest and to deeply characterize them has greatly added to our understanding of biology and disease states. Indeed, cell sorting has become an indispensable ...

cellenONE ® is a comprehensive platform that seamlessly integrates high-accuracy single-cell isolation with precise pico- to nanoliter reagent dispensing. Image-based single-cell sorting and isolation ...

Iowa State University scientists have made a significant breakthrough in scientists' ability to identify specific proteins within individual plant cells. Professor Justin Walley and Christian Montes, ...

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through ...

Ben Orsburn (left) is an Assistant Professor at the University of Pittsburgh (PA, USA) in the Organ Pathobiology and Therapeutics Institute. Ben is a mass spectrometrist whose work revolves around ...

Breakthrough Athena Ion Processor (AIP) delivers up to 35% more peptide and 20% more protein identifications for highest sensitivity proteomics The timsUltra AIP further enhances sensitivity by ...

Discovering passive adaptation To study how cells handle changes in protein production, the researchers used a special fluorescent protein that changes color with time. This made it possible to track ...

A. AIP on timsTOF Ultra 2: Significantly improved peptide and protein identification performance for single-cell proteomics and immunopeptidomics (work-in-progress) The new AIP enables highly ...