Artificial receptors have emerged as a potent class of synthetic molecules that mimic the selective binding properties of natural lectins in recognising carbohydrates. By utilising a diverse array of ...

Carbohydrate recognition is central to a myriad of biological processes including cell signalling, immune response and pathogen detection. Equally, synthetic receptors have emerged as powerful tools ...

Non-immune cells play a crucial and often underappreciated role in host defense against invading pathogens. Beyond serving as passive physical barriers, ...

C-type lectin receptors (CLRs) play central roles in immune recognition, engaging diverse endogenous and exogenous ligands through their C-type lectin-like ...

The opioid-modulating peptides NPFF and RFRP-3 selectively activate NPFFR1 and NPFFR2 through a message–address binding mechanism, where conserved motifs at the peptides’ C-termini engage the ...

Researchers have revealed how the thromboxane A₂ receptor is activated, which could help to inform future heart and lung drug ...

Accurate measurement of HMGB-1, neopterin and sIL-2R supports reliable assessment of immune activation across clinical and ...