Carbohydrate recognition is central to a myriad of biological processes including cell signalling, immune response and pathogen detection. Equally, synthetic receptors have emerged as powerful tools ...

Dendritic cell receptors, in particular C‐type lectins such as DC-SIGN, play a pivotal role in the immune response by recognising and internalising diverse glycan structures present on pathogens. The ...

Cardiovascular diseases (CVDs) remain the leading cause of death worldwide and are now increasingly recognized as conditions with a strong ...

The opioid-modulating peptides NPFF and RFRP-3 selectively activate NPFFR1 and NPFFR2 through a message–address binding mechanism, where conserved motifs at the peptides’ C-termini engage the ...

Researchers have revealed how the thromboxane A₂ receptor is activated, which could help to inform future heart and lung drug ...

Glucagon-like peptide-1 (GLP-1) receptor agonists are incretin analogues that promote glucose-mediated insulin release and are used to treat type 2 diabetes mellitus and obesity. GLP-1 receptor ...

Accurate measurement of HMGB-1, neopterin and sIL-2R supports reliable assessment of immune activation across clinical and ...

Innate immunity is a cornerstone of the body’s immediate defense against cancer, orchestrating the early recognition and response to tumor cells through key ...

Plants must defend themselves against relentless insect herbivores. A new study uncovers how tea plants (Camellia sinensis), one of the world's most valuable crops, activate their immune defenses at ...

AlphaFold has been used to predict how targeted immune receptor engineering could lead to increased disease resistance in plants. Scientists at the University of California, Davis (CA, USA), have ...