Researchers mapped the full biosynthesis of quinine in cinchona trees, identifying key enzymes and intermediates. The discovery enables sustainable lab production of quinine, and related compounds, ...
For over 350 years, quinine and other extracts from the cinchona tree (Cinchona spp.) were the only effective medicines against malaria, a tropical fever caused by single-celled parasites of the genus ...
Newly discovered enzymes found in the cinchona tree play a crucial role in the production of the malaria drug quinine and other important alkaloids. This opens up possibilities for the ...