What is the differential diagnosis for a formerly active and healthy 70-year-old woman with worsening proximal weakness, torticollis, and a widespread raised red rash across her cheeks bilaterally?

Weakness in the legs can be a sign of serious health issues like stroke or cancer. Symptoms like sudden leg weakness, confusion, and dizziness may mean you need medical help right away. Exercise and ...

A 30-year-old African-American woman presented to the emergency department for medical assessment after becoming too weak to walk. She reported proximal muscle aches in both arms and legs, a skin rash ...

Tumors can destroy the blood vessels of muscles even when the muscles are nowhere close to the tumor. That is the key finding of a new study that my colleagues and I recently published in the journal ...

Short-term muscle weakness is common and can be caused by something as simple as a tough workout. However, persistent muscle weakness without apparent cause could indicate an underlying health ...

SMA is a genetic condition that impacts motor neurons, leading to muscle weakness that affects essential functions like breathing and movement. Treatments like Spinraza and Zolgensma can help manage ...

Mr. A appeared very uncomfortable as he sat on the examination table. A vigorous 86-year-old, he always kept his regular appointments for the monitoring of hypertension that was well-controlled with ...

Classic DM (CDM) presents with pathognomonic cutaneous findings and progressive, symmetric proximal muscle weakness. Cutaneous disease usually precedes the appearance of myositis by 3–6 months in ...

Dermatomyositis (DM) affects characteristic areas of the skin and muscles, with different sites of systemic involvement (Figure 1-2). A detailed physical exam is essential for making the correct ...