Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Textbooks often depict proteins in one conformation, but real life, as usual, is much messier. While some proteins have stable, unchanging structures, many others have intrinsically disordered regions ...

JUPITER — Using a blend of computer modeling, structural and cell-based studies, scientists at The Wertheim UF Scripps ...

Targeted protein degradation (TPD) is transforming drug discovery by leveraging the cell’s natural protein disposal systems to eliminate disease-causing proteins. Innovators are making rapid and ...

Jia’s team developed a protocol to improve the screening of protein pockets. This involved identifying the pockets, removing ...

Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In ...

Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), ...

Proteins play a key role in the life sciences -- from basic research and biotechnological applications to the development and manufacturing of pharmaceuticals. Scientists have developed a method that ...