The functioning of neurons, cells that transmit information in the nervous system, heavily relies on the production of ...

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids, but cannot simply accumulate inside the cell forever. Once they have done their ...

Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in our cells. They now show that this complex also controls the processing of ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

Imagine a cancer treatment that precisely targets malignant cells, leaving healthy ones untouched. Consider, also, a cancer treatment that corrects abnormal protein synthesis to produce healthy ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding. Previous studies have shown that protein ...