Calcium (Ca2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum ...

A new research paper was published in Volume 16 of Oncotarget on August 29, 2025, titled "In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma." In this study led by first ...

Membrane protein transport and quality control are central to yeast cell homeostasis, ensuring that proteins reach their correct cellular destinations while aberrant or damaged proteins are ...

Researchers have discovered the first protein quality control system in the yeast nucleus. They report that the system involves an ubiquitin-protein ligase that specifically targets four distinct ...

Researchers have identified a new function of a well-known enzyme: the signal peptidase complex is responsible for the quality control of membrane proteins. The discovery of this new function for a ...

An interdisciplinary team of scientists from Cologne, Heidelberg and Munich have discovered a new function of a well-known enzyme: The signal peptidase complex in the endoplasmic reticulum cleaves ...

A molecular quality-control system in Anopheles mosquitoes-the species responsible for most of the world's malaria cases-is a ...