Proteins are large, complex molecules that carry out the tasks of life. They direct our bodies' activities, organize our thoughts, and defend us against infection, keeping us healthy. But in their ...

Structural mass spectrometry has emerged as a powerful approach to elucidate the three‐dimensional conformations of proteins and their complexes under near‐physiological conditions. In particular, ...

Just like workers need the right environment to efficiently perform their tasks, proteins require placement within specific cellular compartments to function properly. Therefore, understanding the ...

Technological advances in mass spectrometry are aiding researchers to image and characterize protein and other cellular components with increasing resolution. Using native ambient mass spectrometry ...

Nicoya Lifesciences is launching FastHDX, a hydrogen-deuterium exchange mass spectrometry platform to measure protein ...

Antibody arrays: removal of high abundance proteins is not required, but antibody availability limits protein detection. Mass spectrometry: “hypothesis-free” protein detection is affected by high ...

A screening technique commonly used in drug discovery can yield important details about the actions of molecular ‘glues’ in protein interactions. Molecular glues are emerging as powerful therapeutic ...

This episode of the Pharmaron DMPK Insights Podcast Series features Scott Summerfield (Executive Director of Metabolism at Pharmaron) and John Mehl (consultant and previous director at GSK, and ...

As our bodies run multiple parallel processes, they shuttle a flurry of messages around inside—often as protein-metabolite interactions (PMIs), where small molecules bind to a protein and initiate or ...

Emerging mass spectrometry technologies integrating ion mobility, TIMS–PASEF, and real-time search are enhancing sensitivity, ...

Built on groundbreaking research from Israel ’s Weizmann Institute of Science, Promise Bio developed the first cloud-based platform for broad epiproteomics, helping researchers uncover disease ...