Researchers have developed a novel method of adding polyethylene glycol molecules to engineered groups of messenger RNAs called 'mRNA polyplexes', which enable the cells that receive them to produce ...

Researchers have incorporated a base into mRNA that is not naturally present in the human body, producing mRNA that has decreased cytotoxicity compared to unmodified mRNA. Modified mRNA is more stable ...

Researchers have discovered that a chemical modification to the synthetic messenger RNA used in therapeutics can cause the cell’s machinery to misread its instructions and result in unintended immune ...

Researchers have discovered that misreading of therapeutic mRNAs by the cell's decoding machinery can cause an unintended immune response in the body. They have identified the sequence within the mRNA ...

In a recent review published in Nature Medicine, researchers presented challenges related to the clinical translation of messenger ribonucleic acid (mRNA) technology, recent innovations, and future ...

mRNA vaccines are a novel type of vaccine that use messenger RNA (mRNA) to induce an immune response against a specific pathogen. Unlike traditional vaccines that use weakened or inactivated viruses ...

Researchers from Tokyo Medical and Dental University (TMDU) have developed a novel method for chemically modifying engineered messenger RNA molecules, allowing greater control of their biological ...

Medicine can help to treat certain illnesses; for example, antibiotics can help overcome infections, but a new, promising field of medicine involves providing our body with the "blueprint" for how to ...