ADME is the abbreviation for Absorption, Distribution, Metabolism and Excretion. ADME studies are designed to investigate how a chemical (e.g., a drug compound) is processed by a living organism.

Drug discovery technology and information company Cyprotex has launched Cloe Gateway, a web portal for access to drug discovery services. The services are available on a pay-per-use basis. The portal ...

ADME is an abbreviation in pharmacokinetics and pharmacology that stands for absorption, distribution, metabolism, and elimination of chemicals and drugs to define impact in the human body. Toxicology ...

This is a preview. Log in through your library . Abstract Studies of absorption, distribution, metabolism, and elimination (ADME) have long been recognized as important in the evaluation of the ...

The field of pharmacokinetics attempts to describe the bodily disposition of drugs in terms of numerical parameters that are calculated from plasma concentrations obtained at time points after drug ...

Variability in pharmacokinetics and drug response is shaped by single-nucleotide variants (SNVs) as well as copy-number variants (CNVs) in genes with importance for drug absorption, distribution, ...

In a study posted to the bioRxiv* preprint server, researchers studied the preclinical pharmacokinetics (PK) and in vitro absorption, distribution, metabolism, and elimination (ADME) properties of ...

It may sound harsh, but drug candidates that are bound to be poor performers should be identified sooner rather than later—and ruthlessly eliminated from development. Granted, early in development, ...

Collaboration aims to create the first “organ-on-a-chip” system specifically designed for human PK predictions WOBURN, Mass.--(BUSINESS WIRE)-- Javelin Biotech (“Javelin”) today announces a three-year ...