The use of oligonucleotides as therapeutic agents is of great interest, particularly when it comes to siRNA and antisense oligonucleotides. However, the difficulty of targeting the right organ and ...

Last week, at the TIDES conference in Boston, Martin Deetz, PhD, research laureate at DuPont, and his colleagues presented a poster on using reverse-phase high-performance chromatography (RP-HPLC) to ...

Oligonucleotides are short single- or double-stranded nucleic acid polymers that interact with target RNA or DNA to elicit biological responses. There are currently 19 FDA approved oligonucleotide ...

Oligonucleotide therapies — engineered strands of DNA or RNA — are transforming modern medicine. These cutting-edge treatments bring a new level of precision in combating disease by targeting specific ...

UPPSALA, Sweden, Oct. 20, 2021 /PRNewswire/ -- Biotage AB (publ) ("Biotage") has today entered into an agreement to acquire all outstanding shares in the privately held company ATDBio Limited ("ATDBio ...

Therapeutic oligonucleotides act on different stages of pathological gene expression. Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription ...

HOLLISTON, Mass.--(BUSINESS WIRE)--Oligo Factory, a leading manufacturer of high-quality oligonucleotides at scale, announces today that it is compliant with current Good Manufacturing Practices (GMP) ...

Variations in conjugation chemistry conditions can lead to differences in stoichiometries and, ultimately, impact drug safety and efficacy. Therefore, there is an urgent need to measure multiple ...

The ebook also details the helpful role MGB Probes can play when using crude DNA alongside the latest ultra-fast purification methods that can deliver high-purity DNA with high-yield within 5 minutes.

RNA and DNA therapies are revolutionizing the field of medicine. These therapies target specific genes which are then silenced, expressed, or edited to treat various diseases. The advancement of ...