Nucleic acid synthesis underpins life’s vital processes, from replication and transcription to the regulation of gene expression, while polymerase enzymology explores the molecular mechanisms by which ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

A new platform for making oligonucleotides offers chemists a way to plug in five types of nucleoside connections, so they can tailor properties of oligonucleotide therapeutics. These short DNA or RNA ...