Nucleic acids may be labeled at their 3’ end, 5’ end, or throughout the molecule, depending on the desired application. Myriad of enzymatic or chemical methods are utilized to generate nucleic acids ...
NEW YORK--(BUSINESS WIRE)--Enzo Biochem, Inc. (NYSE:ENZ), an integrated diagnostics and therapeutics company, today announced the issuance of U.S. Patent No. 10,323,272 entitled Nucleic Acid Probes ...
Applications of PNA include altering gene expression, serving as inhibitors and promoters, antigene and antisense therapeutics, anticancer agents, antiviral agents, antibacterial and antiparasitic ...
DNA hybridization thermodynamics is critical for accurate design of oligonucleotides for biotechnology and nanotechnology applications, but parameters currently in use are inaccurately extrapolated ...
In this paper we demonstrate that peptide nucleic acids (PNAs) are excellent probes able to detect the W1282X point mutation of the cystic fibrosis (CF) gene when biospecific interaction analysis (BIA ...
Scientists have invented and developed a powerful nanomaterial that could revolutionize biomedicine: spherical nucleic acids (SNAs). The novel arrangement of nucleic acids imparts interesting chemical ...
A few years back, the 50th anniversary of the discovery of the structure of the DNA double helix by biologists James D. Watson and Francis H. C. Crick was grandly celebrated. In fact, it's a double ...