After the initial reports of the association of fetal trisomy 21 with low maternal serum alpha fetoprotein (MSAFP) levels in retrospective studies in 1984, we began using low MSAFP levels as a means ...
Second trimester MSAFP screening for low values is proving valuable in the detection of fetal chromosome defects in women < 35 yrs. of age. Detection prior to 16 wks. would be desirable. To determine ...
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