According to an international multicenter study, CD2-negative mast cells are associated with significantly reduced overall survival in patients with SM. Patients with CD2-negative mast cells have ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

What Is Advanced Systemic Mastocytosis? Mast cells, found in connective tissue throughout the body, are a type of white blood cell that helps the immune system function properly and protect against ...

Chronic urticaria (CU) is a dermatological condition characterized by recurrent wheals (hives), angioedema (deep tissue swelling), or both, persisting for over 6 weeks. 1 Unlike acute urticaria, which ...

Depending on one's perspective, "mast cell activation syndrome (MCAS)" is either a relatively rare, narrowly defined severe allergic condition or a vastly under-recognized underlying cause of multiple ...