A DNA nanostructure flips lipids from one side of a lipid bilayer to the other more than 1,000 times as fast as natural enzymes called scramblases, researchers report (Nat. Commun. 2018, DOI: ...

During the last 50 years, an abundance of data has been gathered on the function of lipids as a source of energy, as building blocks, and as signaling molecules in living systems. Lipid-signaling ...

Two teams of researchers have independently converged on a new drug target for Parkinson’s disease. Two studies published last week, one from the biotech start-up Yumanity Therapeutics and another led ...

Most of us don't give much thought to lipids except in terms of their being a component of fat (and best avoided, accordingly). But they're essential components of all membranes in cells, and ...

A team led by scientists at The Scripps Research Institute (TSRI) has identified an enzyme that produces a class of inflammatory lipid molecules in the brain. Abnormally high levels of these molecules ...

Using a mouse heart attack model, researchers have shown that knocking out one particular lipid-modifying enzyme, along with a short-term dietary excess of a certain lipid, can improve post-heart ...

Cells of all life forms are surrounded by a membrane that is made of phospholipids. One of these are the cardiolipins, which form a separate class due to their unique structure. When studying the ...

Reducing high concentrations of a fatty molecule that is commonly found in people with diabetes and nonalcoholic fatty liver disease rapidly improves insulin sensitivity, research shows. Reducing high ...

Adding long-chain fatty acids can thicken cell membranes and alter the activity of a key enzyme, as LMU scientists have demonstrated in cell cultures. A characteristic feature of Alzheimer's disease ...

IN analysis of the sequence of enzyme differentiation it was found that several enzymes are lipid-bound and that tissue differentiation is determined by the distribution of enzymes in a lipid-bound ...