Nanoparticles have once again reached the spotlight, this time as a critical tool to combat the spread of covid-19. In this particular case, messenger ribonucleic acid (mRNA) encapsulated in lipid ...
eTheRNA Manufacturing, a specialist CDMO member of the Belgian eTheRNA group, is introducing a new Lipid Nanoparticle (LNP) formulation development and production service to support the discovery and ...
In a recent study published in PNAS, researchers presented a scalable lipid nanoparticle (LNP) production (SCALAR) platform to produce high-throughput lipid nanoparticles on one microfluidic chip and ...
Lipid nanoparticle formulation has increased over the past two decades. LNPs have proven to be effective nano-based delivery vehicles for cytotoxic chemotherapeutic drugs, nucleic acid therapies and ...
Cancer cells have softer membranes than healthy cells. New nanoparticles exploit this physical difference to fuse selectively ...
A review maps high throughput strategies that link automation, microfluidics, and barcoding into a unified pipeline, enabling faster, more predictive lipid nanoparticle development for genetic ...
Liposomes and lipid nanoparticles (LNPs) are versatile drug delivery systems that allow precise control over composition, morphology, and structure, tailoring these features to meet specific ...
From vaccines to personalized cancer therapies, scientists are studying the use of mRNA across many clinical applications. However, there are several factors that are unique to mRNA drug product ...
The latest short science news items from C&EN. A complicated sequence of events follows once an RNA drug is injected into the body. After the lipid-packaged RNA arrives at a cell, it pushes through ...
An illustration showing a lipid nanoparticle containing messenger RNA enter a cell. A lipid nanoparticle (LNP) containing messenger RNA (mRNA) enters a cell through an endosome (right). When the LNP ...