Type 1 diabetes is a disease in which the body mistakenly attacks itself as the immune system destroys the pancreas's insulin-producing cells. Why the immune system turns against these cells remains ...

The image shows Langerhans islets after chronic intermittent fasting. On the left those of an adult animal, on the right those of a young animal. The beta cells of the pancreatic Langerhans’ islets ...

Diabetes develops when the body fails to manage its blood glucose levels. One form of diabetes causes the body to not produce insulin at all. Called Type 1 diabetes, or T1D, this autoimmune disease ...

Igniting hope for a new-and-improved stem cell therapy for type 1 diabetes, scientists have reported a method for creating insulin-producing cells that reverse diabetes in mice and may overcome some ...

Researchers at Umeå University have conducted a unique three-dimensional mapping of an entire human pancreas. The study shows that insulin-producing cells can remain long after the onset of type 1 ...

Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies. Researchers led by ...

Islet of langerhans, light micrograph. This structure (centre), found in the pancreas, secretes the hormones insulin and glucagon, which control blood sugar levels. Magnification: x200 when printed at ...

ORLANDO, Fla — Stem cell–derived beta-cell replacement therapy continues to show benefit in people with type 1 diabetes at a high risk for severe hypoglycemia. Of a total 17 patients who received a ...

Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimislecel ...

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance, published in ...