For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...
Formation of the energy-producing machinery in the proximal tubule of the nephron is an essential step in differentiation. The authors show that mitochondrial localization depends on LRRK2, the ...
Traditional animal models and simplified cell cultures often fail to capture human biology, limiting progress in biomedical research and drug development. Emerging microfluidic "Organ-on-Chip" ...
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