In 1993, 25 years after her family launched their foundation, the group of scientists they supported finally identified the ...

Huntington’s disease (HD) is one of those rare conditions that affects not just the patient but the entire family—medically, emotionally and genetically. This inherited brain disorder causes gradual ...

Gene therapy is becoming a powerful way to treat challenging diseases that don’t respond to traditional treatments, and researchers now report the first success in modifying genes to slow Huntington’s ...

ST. LOUIS — Scientists may have reached a breakthrough in the fight against Huntington’s disease, a rare and fatal inherited brain disorder with no cure. For the first time, a gene therapy has been ...

In the spring of 1872, a young physician in New York published a paper about "chorea," a condition that caused people to lose their ability to speak, control movements, and behave. He noted that the ...

Researchers have implicated a new gene in the progression of Huntington's disease in a brain organoid model. The gene may contribute to brain abnormalities much earlier than previously thought. Six ...

A decade ago, UB researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease? They found that HTT is something like ...