RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage. Type V CRISPR-Cas (Cas12) systems, in particular, ...

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and ...

The beginning of life on Earth and its evolution over billions of years continue to intrigue researchers worldwide. The central dogma or the directional flow of genetic information from a deoxyribose ...

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for ...

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

By Dr. Priyom Bose, Ph.D. A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life, offering fresh insight into how a father’s age may influence the ...

MYC‑driven tumors silence innate immune alarms by clearing R‑loop–derived signals, exposing a new therapeutic angle for targeting MYC without broad inhibition.

Programmable nucleic acid nanoparticles boost vaccine immune responses as effectively as standard adjuvants in mice while avoiding the autoimmune risks that limit existing alternatives.