CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage. Type V CRISPR-Cas (Cas12) systems, in particular, ...

Ribonucleic acid (RNA) is critical in regulating plant gene expression, growth, and stress responses, with structural motifs often determining functionality. However, identifying functional RNA motifs ...

Researchers identify a shared RNA-protein interaction that could lead to broad-spectrum antiviral treatments for enteroviruses ...

Researchers from Tokyo University of Science have engineered a ribozyme structure which mimics the early RNA world and provides novel insights on the role of RNA in primitive life, to its various real ...

Advancing RNA therapeutics depends on understanding two critical questions: Where do drug candidates go, and what do they do ...

A pioneering Artificial Intelligence (AI) powered model able to understand the sequences and structure patterns that make up the genetic “language” of plants, has been launched by a research ...

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

In a recent study published in the journal Nature Methods, a group of researchers developed a novel method called Ribonucleic Acid (RNA) High-Order Folding Prediction Plus (RhoFold+). This deep ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

The origin of life continues to remain a matter of debate. The ribonucleic acid (RNA) world hypothesis proposes that 'ribozymes' which store genetic information and possess catalytic functions may ...