The interplay between G protein-coupled receptors (GPCRs) and fatty acid metabolism is emerging as a pivotal aspect in the pathogenesis and treatment of type 2 diabetes. Receptors such as free fatty ...

Dysregulation of fatty acid metabolism in diabetes leads to changes in fatty acid profiles, abnormal lipid accumulation, and increased oxidative stress. These changes contribute to microvascular ...

In an article in Nature Microbiology, researchers investigated the mechanism behind the preference for sugar and its link to diabetes, focusing on the role of a free fatty acid receptor and gut ...

Purdue University’s James Markworth, assistant professor of animal sciences, and PhD student Xinyue Lu observe results of immunofluorescent staining of a cross-sectional sample of skeletal muscle ...

Metabolic Dysfunction-Associated Steatotic Liver Disease（MASLD） is characterized by excessive accumulation of lipids in hepatocytes and is closely associated with the rapid rise in insulin resistance, ...

Short-chain fatty acids (SCFAs) are an important class of biologically active substances produced in the gut, specifically by the action of gut bacteria on plant-derived foods containing fiber that is ...