Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why ...

Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

Two to three weeks after conception, an embryo faces a critical point in its development. In the stage known as gastrulation, the transformation of embryonic cells into specialized cells begins. This ...

Researchers have used stem cells to develop new human embryolike structures that model the earliest stages of fetal development so realistically that they even secrete hormones that can turn a lab ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...

A recent Nature study evaluates post-implantation development in humans using embryo-like models based on genetically unmodified human naïve embryonic stem cells (ESCs). Study: Complete human day 14 ...

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some ...

When Berna Sozen, PhD, assistant professor of Developmental Stem Cell Biology at Yale, was in her first weeks of pregnancy, she couldn’t help but wonder about what exactly was going on in the “black ...

Scientists have grown a scalable new embryo-like model that unshrouds some mysteries of early human development, including blood cell formation, or hematopoiesis—a first for the field. In an article ...