Researchers report that they are at the forefront of discovering and mapping out the complexities of the structures involved in a process of pri-miRNA biogenesis. For the first time, the team has ...
An insightful molecular mechanism of how Microprocessor has been revealed by scientists: the DROSHA-DGCR8 complex, precisely determines cleavage sites on miRNA-containing primary transcripts allowing ...
The RNA endonuclease Drosha is required for myelopoiesis by its direct cleavage of stem-loop structures in mRNAs encoding Myl9 and Todr1. miRNAs are small RNAs of approximately 22 nucleotides that ...
Scientists working at the IBS Center for RNA Research in South Korea are at the forefront of discovering and mapping out the complexities of the structures involved in this process of pri-miRNA ...
Recently, a nucleolar proteomic screen expanded on the mechanism through which ARF controls rRNA synthesis by identifying a novel relationship between ARF and the DEAD-box RNA helicase, DDX5. 11 Basal ...
TDP-43 shepherds select microRNAs through their maturation process from nuclear transcripts to grown-up regulatory fragments set loose in the cytoplasm, according to a paper in the February 9 ...
video: Scientists working at the IBS Center for RNA Research in South Korea are at the forefront of discovering and mapping out the complexities of the structures involved in this process of pri-miRNA ...
Our bodies are made up of many different types of cells, with each of their identities determined by different gene expression. Cancer and genetic diseases occur when this gene expression goes wrong.
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