Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and ...

As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, self-perpetuating state of inflammation. Emerging work now suggests that aging immune ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Xiaoqi Feng holding a male liverwort in her lab at the Institute of Science and Technology Austria (ISTA). The group of Xiaoqi Feng at the Institute of Science and Technology Austria (ISTA) uses this ...

Mitochondria are well known as the powerhouses of the cell because of their energy generating capabilities. These little organelles are very special, because they also carry their own tiny little ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

EVOFLUx uses DNA methylation fluctuations as molecular barcodes to trace tumor evolution, offering insights into growth, treatment resistance, and prognosis. The method requires only bulk methylation ...