ALTHOUGH nucleotides other than those of adenyl origin have been isolated from muscle 1, physiologists, when considering the events associated with the contraction-relaxation cycle, have assigned a ...

To grow and multiply efficiently, bacteria must coordinate cell division with chromosome segregation. Key to this process is a protein called Nucleoid Occlusion Factor or Noc. A small and abundant ...

This is a preview. Log in through your library . Abstract During brief (30-min) incubations, isolated rat retinas accumulated [3 H]cytidine, converted it to cytidine triphosphate (CTP), and ...

PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...

The Nature Index 2024 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

After an eight-year odyssey, the first cytidine triphosphate synthase 1 (CTPS1) inhibitor has entered the clinic, with Step Pharma SAS announcing it has simultaneously begun studies in the U.S. and ...

In 2010, cytidine triphosphate synthase (CTPS) was independently discovered by three research groups. CTPS is a metabolic enzyme that is responsible for the de novo synthesis of nucleotide cytidine ...

DUBLIN – Step Pharma SAS closed a €35 million (US$41.5 million) series B round to move its first-in-class cytidine triphosphate synthase 1 (CTPS1) inhibitor into clinical trials in patients with ...