Nanopores (otherwise known as transmembrane β-barrel pores (TMBs)) are perhaps best known for their role in the sequencing of nucleic acids—both DNA and RNA. They can also be used to sequence peptides ...

The Nobel Prizes are embracing the AI hype. A day after the Physics prize was given to two scientists for foundational work on machine learning, the Nobel Prize in Chemistry has been awarded to three ...

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), ...

A biochemist at the University of Washington School of Medicine has won the Nobel Prize in Chemistry for his groundbreaking work in computational protein design. When David Baker first set out decades ...

Three scientists were named winners of the 2024 Nobel Prize in Chemistry for their innovations in the fields of computational protein design and structure prediction. One half of the prize was awarded ...

Using artificial intelligence (AI), a team of scientists led by Nobel Prize winner David Baker at the University of Washington has created a computational method for generating proteins that bind and ...

Jue Wang (left) is a research scientist and one of the scientific leads of the protein design team at Google DeepMind (London, UK). Before joining DeepMind, Jue was a postdoc with David Baker ...

Using the MProt-DPO framework, scientists created synthetic versions of malate dehydrogenase that preserve the protein’s critical structure and key binding areas. Harnessing the power of artificial ...

Matthew Addicoat receives funding from EPSRC and the Royal Society. Using computers to carry out protein design and for predicting protein structures are two sides of the same coin. They are ...

New research represents a notable step forward in designing enzymes from scratch. With their approach, the authors designed an enzyme that uses a covalent intermediate to catalyze a two-step reaction, ...