From structure confirmation to methodology improvements, making complex natural products has driven innovation in organic ...

Surface model of SpCas9–reverse transcriptase–pegRNA–target DNA complex. The prime editor, composed of a SpCas9 and a reverse transcriptase, reverse transcribes template sequence in pegRNA, resulting ...

This whopping piece of molecular architecture incorporates 2,712 atoms across 12 identical macrocycles held together by 144 hydrogen bonds (Nature 2025, DOI: 10.1038/s41586-024-08266-3). It’s not the ...

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...

Cancer diagnoses traditionally require invasive or labor-intensive procedures such as tissue biopsies. Researchers at the Ludwig-Maximilians-Universität München (LMU) have now reported on a method ...